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Altered Dopamine and Serotonin Metabolism in Motorically Asymptomatic R6/2 Mice

The pattern of cerebral dopamine (DA) abnormalities in Huntington disease (HD) is complex, as reflected by the variable clinical benefit of both DA antagonists and agonists in treating HD symptoms. In addition, little is known about serotonin metabolism despite the early occurrence of anxiety and de...

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Detalles Bibliográficos
Autores principales: Mochel, Fanny, Durant, Brandon, Durr, Alexandra, Schiffmann, Raphael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069081/
https://www.ncbi.nlm.nih.gov/pubmed/21483838
http://dx.doi.org/10.1371/journal.pone.0018336