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Altered Dopamine and Serotonin Metabolism in Motorically Asymptomatic R6/2 Mice
The pattern of cerebral dopamine (DA) abnormalities in Huntington disease (HD) is complex, as reflected by the variable clinical benefit of both DA antagonists and agonists in treating HD symptoms. In addition, little is known about serotonin metabolism despite the early occurrence of anxiety and de...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069081/ https://www.ncbi.nlm.nih.gov/pubmed/21483838 http://dx.doi.org/10.1371/journal.pone.0018336 |