The Cyclophilin-Binding Agent Sanglifehrin A Is a Dendritic Cell Chemokine and Migration Inhibitor

Sanglifehrin A (SFA) is a cyclophilin-binding immunosuppressant but the immunobiology of action is poorly understood. We and others have reported that SFA inhibits IL-12 production and antigen uptake in dendritic cells (DC) and exhibits lower activity against lymphocytes. Here we show that SFA suppr...

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Detalles Bibliográficos
Autores principales: Immecke, Sabrina N., Baal, Nelli, Wilhelm, Jochen, Bechtel, Juliane, Knoche, Angela, Bein, Gregor, Hackstein, Holger
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069092/
https://www.ncbi.nlm.nih.gov/pubmed/21483789
http://dx.doi.org/10.1371/journal.pone.0018406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069092/
https://www.ncbi.nlm.nih.gov/pubmed/21483789
http://dx.doi.org/10.1371/journal.pone.0018406

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