Cargando…

AMPK Regulates Circadian Rhythms in a Tissue- and Isoform-Specific Manner

BACKGROUND: AMP protein kinase (AMPK) plays an important role in food intake and energy metabolism, which are synchronized to the light-dark cycle. In vitro, AMPK affects the circadian rhythm by regulating at least two clock components, CKIα and CRY1, via direct phosphorylation. However, it is not k...

Descripción completa

Detalles Bibliográficos
Autores principales: Um, Jee-Hyun, Pendergast, Julie S., Springer, Danielle A., Foretz, Marc, Viollet, Benoit, Brown, Alexandra, Kim, Myung K., Yamazaki, Shin, Chung, Jay H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069094/
https://www.ncbi.nlm.nih.gov/pubmed/21483791
http://dx.doi.org/10.1371/journal.pone.0018450