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AMPK Regulates Circadian Rhythms in a Tissue- and Isoform-Specific Manner
BACKGROUND: AMP protein kinase (AMPK) plays an important role in food intake and energy metabolism, which are synchronized to the light-dark cycle. In vitro, AMPK affects the circadian rhythm by regulating at least two clock components, CKIα and CRY1, via direct phosphorylation. However, it is not k...
Autores principales: | Um, Jee-Hyun, Pendergast, Julie S., Springer, Danielle A., Foretz, Marc, Viollet, Benoit, Brown, Alexandra, Kim, Myung K., Yamazaki, Shin, Chung, Jay H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069094/ https://www.ncbi.nlm.nih.gov/pubmed/21483791 http://dx.doi.org/10.1371/journal.pone.0018450 |
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