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Mild Mitochondrial Uncoupling and Calorie Restriction Increase Fasting eNOS, Akt and Mitochondrial Biogenesis

Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR). Since treatment of mice with dinitrophenol (DNP) promotes health and lifespan benefits similar to those observed in CR, we hypothesized that it coul...

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Detalles Bibliográficos
Autores principales: Cerqueira, Fernanda M., Laurindo, Francisco R. M., Kowaltowski, Alicia J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069103/
https://www.ncbi.nlm.nih.gov/pubmed/21483800
http://dx.doi.org/10.1371/journal.pone.0018433