The SUMO Isopeptidase Ulp2p Is Required to Prevent Recombination-Induced Chromosome Segregation Lethality following DNA Replication Stress

SUMO conjugation is a key regulator of the cellular response to DNA replication stress, acting in part to control recombination at stalled DNA replication forks. Here we examine recombination-related phenotypes in yeast mutants defective for the SUMO de-conjugating/chain-editing enzyme Ulp2p. We fin...

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Detalles Bibliográficos
Autores principales: Lee, Ming-Ta, Bakir, Abla A., Nguyen, Kristen N., Bachant, Jeff
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069114/
https://www.ncbi.nlm.nih.gov/pubmed/21483811
http://dx.doi.org/10.1371/journal.pgen.1001355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069114/
https://www.ncbi.nlm.nih.gov/pubmed/21483811
http://dx.doi.org/10.1371/journal.pgen.1001355

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