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Contractility Dominates Adhesive Ligand Density in Regulating Cellular De-adhesion and Retraction Kinetics
Cells that are enzymatically detached from a solid substrate rapidly round up as the tensile prestress in the cytoskeleton is suddenly unopposed by cell–ECM adhesions. We recently showed that this retraction follows sigmoidal kinetics with time constants that correlate closely with cortical stiffnes...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069333/ https://www.ncbi.nlm.nih.gov/pubmed/21046466 http://dx.doi.org/10.1007/s10439-010-0195-z |