On the Stereochemistry of 2-Hydroxyethylphosphonate Dioxygenase

[Image: see text] Stereochemical investigations have shown that the conversion of 2-hydroxyethylphosphonate to hydroxymethylphosphonate by the enzyme HEPD involves removal of the pro-S hydrogen at C2 and, surprisingly, the loss of stereochemical information at C1. As a result, the mechanisms previou...

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Detalles Bibliográficos
Autores principales: Whitteck, John T., Malova, Petra, Peck, Spencer C., Cicchillo, Robert M., Hammerschmidt, Friedrich, van der Donk, Wilfred A.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069692/
https://www.ncbi.nlm.nih.gov/pubmed/21381767
http://dx.doi.org/10.1021/ja1113326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069692/
https://www.ncbi.nlm.nih.gov/pubmed/21381767
http://dx.doi.org/10.1021/ja1113326

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