A Fungal Metabolite Asperparaline A Strongly and Selectively Blocks Insect Nicotinic Acetylcholine Receptors: The First Report on the Mode of Action

Asperparalines produced by Aspergillus japonicus JV-23 induce paralysis in silkworm (Bombyx mori) larvae, but the target underlying insect toxicity remains unknown. In the present study, we have investigated the actions of asperparaline A on ligand-gated ion channels expressed in cultured larval bra...

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Detalles Bibliográficos
Autores principales: Hirata, Koichi, Kataoka, Saori, Furutani, Shogo, Hayashi, Hideo, Matsuda, Kazuhiko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069973/
https://www.ncbi.nlm.nih.gov/pubmed/21483774
http://dx.doi.org/10.1371/journal.pone.0018354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069973/
https://www.ncbi.nlm.nih.gov/pubmed/21483774
http://dx.doi.org/10.1371/journal.pone.0018354

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