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Role of Sema4C in TGF-β1-induced mitogen-activated protein kinase activation and epithelial–mesenchymal transition in renal tubular epithelial cells

Background. The p38 mitogen-activated protein kinase (p38 MAPK) is an important intracellular signal transduction pathway involved in TGF-β1-induced epithelial–mesenchymal transition (EMT). Sema4C, a member of the semaphorin family, was found to be essential for the activation of p38 MAPK. However,...

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Detalles Bibliográficos
Autores principales: Zeng, Rui, Han, Min, Luo, Yun, Li, Caixia, Pei, Guangchang, Liao, Wenhui, Bai, Shoujun, Ge, Shuwang, Liu, XiaoCheng, Xu, Gang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070071/
https://www.ncbi.nlm.nih.gov/pubmed/20959347
http://dx.doi.org/10.1093/ndt/gfq619