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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

CRISPR/Cas systems constitute a widespread class of immunity systems that protect bacteria and archaea against phages and plasmids, and commonly use repeat/spacer-derived short crRNAs to silence foreign nucleic acids in a sequence-specific manner. Although the maturation of crRNAs represents a key e...

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Detalles Bibliográficos
Autores principales: Deltcheva, Elitza, Chylinski, Krzysztof, Sharma, Cynthia M., Gonzales, Karine, Chao, Yanjie, Pirzada, Zaid A., Eckert, Maria R., Vogel, Jörg, Charpentier, Emmanuelle
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070239/
https://www.ncbi.nlm.nih.gov/pubmed/21455174
http://dx.doi.org/10.1038/nature09886