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The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine

Pyrrolysine, the 22(nd) amino acid to be found in the natural genetic code1–4, is necessary for all known pathways of methane formation from methylamines5,6. The residue is comprised of a methylated pyrroline carboxylate in amide linkage to the ε-amino group of L-lysine2,7,8. The three different met...

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Detalles Bibliográficos
Autores principales: Gaston, Marsha A., Zhang, Liwen, Green-Church, Kari B., Krzycki, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070376/
https://www.ncbi.nlm.nih.gov/pubmed/21455182
http://dx.doi.org/10.1038/nature09918