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Elementary signaling modes predict the essentiality of signal transduction network components
BACKGROUND: Understanding how signals propagate through signaling pathways and networks is a central goal in systems biology. Quantitative dynamic models help to achieve this understanding, but are difficult to construct and validate because of the scarcity of known mechanistic details and kinetic p...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070649/ https://www.ncbi.nlm.nih.gov/pubmed/21426566 http://dx.doi.org/10.1186/1752-0509-5-44 |