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Sphingomyelin synthase overexpression increases cholesterol accumulation and decreases cholesterol secretion in liver cells

BACKGROUND: Studies have shown that plasma high density lipoprotein cholesterol levels are negatively correlated with the development of atherosclerosis, whereas epidemiological studies have also shown that plasma sphingomyelin level is an independent risk factor for atherosclerosis. METHODS: To eva...

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Detalles Bibliográficos
Autores principales: Yan, Nianlong, Ding, Tingbo, Dong, Jibin, Li, Yue, Wu, Manping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070670/
https://www.ncbi.nlm.nih.gov/pubmed/21418611
http://dx.doi.org/10.1186/1476-511X-10-46