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Correlation of SHOX2 Gene Amplification and DNA Methylation in Lung Cancer Tumors

BACKGROUND: DNA methylation in the SHOX2 locus was previously used to reliably detect lung cancer in a group of critical controls, including 'cytologically negative' samples with no visible tumor cell content, at a high specificity based on the analysis of bronchial lavage samples. This st...

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Detalles Bibliográficos
Autores principales: Schneider, Katja U, Dietrich, Dimo, Fleischhacker, Michael, Leschber, Gunda, Merk, Johannes, Schäper, Frank, Stapert, Henk R, Vossenaar, Erik R, Weickmann, Sabine, Liebenberg, Volker, Kneip, Christoph, Seegebarth, Anke, Erdogan, Fikret, Rappold, Gudrun, Schmidt, Bernd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070682/
https://www.ncbi.nlm.nih.gov/pubmed/21426551
http://dx.doi.org/10.1186/1471-2407-11-102