Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer

BACKGROUND: Considerable variation in intravenous 5-fluorouracil (5-FU) metabolism can occur due to the wide range of dihydropyrimidine dehydrogenase (DPD) enzyme activity, which can affect both tolerability and efficacy. The oral fluoropyrimidine tegafur-uracil (UFT) is an effective, well-tolerated...

Descripción completa

Detalles Bibliográficos
Autores principales: Cellier, Patrice, Leduc, Bernard, Martin, Laurent, Vié, Brigitte, Chevelle, Christian, Vendrely, Véronique, Salemkour, Augustin, Carrie, Christian, Calais, Gilles, Burtin, Pascal, Campion, Loïc, Boisdron-Celle, Michèle, Morel, Alain, Berger, Virginie, Gamelin, Erick
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070684/
https://www.ncbi.nlm.nih.gov/pubmed/21410976
http://dx.doi.org/10.1186/1471-2407-11-98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070684/
https://www.ncbi.nlm.nih.gov/pubmed/21410976
http://dx.doi.org/10.1186/1471-2407-11-98

Ejemplares similares