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CTLA4 is expressed on mature dendritic cells derived from human monocytes and influences their maturation and antigen presentation

BACKGROUND: Dendritic cells (DCs) initiate immune responses through their direct interaction with effector cells. However, the mechanism by which DC activity is regulated is not well defined. Previous studies have shown that CTLA4 on T cells regulates DCs function by "cross-talk". We inves...

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Detalles Bibliográficos
Autores principales: Wang, Xiong B, Fan, Zhong Z, Anton, Doina, Vollenhoven, Annika V, Ni, Zhen H, Chen, Xiao F, Lefvert, Ann K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070687/
https://www.ncbi.nlm.nih.gov/pubmed/21414236
http://dx.doi.org/10.1186/1471-2172-12-21