Single Molecule In Vivo Analysis of Toll-Like Receptor 9 and CpG DNA Interaction

Toll-like receptor 9 (TLR9) activates the innate immune system in response to oligonucleotides rich in CpG whereas DNA lacking CpG could inhibit its activation. However, the mechanism of how TLR9 interacts with nucleic acid and becomes activated in live cells is not well understood. Here, we report...

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Detalles Bibliográficos
Autores principales: Chen, Jiji, Nag, Suman, Vidi, Pierre-Alexandre, Irudayaraj, Joseph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070698/
https://www.ncbi.nlm.nih.gov/pubmed/21483736
http://dx.doi.org/10.1371/journal.pone.0017991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070698/
https://www.ncbi.nlm.nih.gov/pubmed/21483736
http://dx.doi.org/10.1371/journal.pone.0017991

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