Cargando…
Single Molecule In Vivo Analysis of Toll-Like Receptor 9 and CpG DNA Interaction
Toll-like receptor 9 (TLR9) activates the innate immune system in response to oligonucleotides rich in CpG whereas DNA lacking CpG could inhibit its activation. However, the mechanism of how TLR9 interacts with nucleic acid and becomes activated in live cells is not well understood. Here, we report...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070698/ https://www.ncbi.nlm.nih.gov/pubmed/21483736 http://dx.doi.org/10.1371/journal.pone.0017991 |