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Role of Heparanase on Hepatic Uptake of Intestinal Derived Lipoprotein and Fatty Streak Formation in Mice

BACKGROUND: Heparanase modulates the level of heparan sulfate proteoglycans (HSPGs) which have an important role in multiple cellular processes. Recent studies indicate that HSPGs have an important function in hepatic lipoprotein handling and processes involving removal of lipoprotein particles. PRI...

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Detalles Bibliográficos
Autores principales: Planer, David, Metzger, Shulamit, Zcharia, Eyal, Wexler, Isaiah D., Vlodavsky, Israel, Chajek-Shaul, Tova
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070732/
https://www.ncbi.nlm.nih.gov/pubmed/21483695
http://dx.doi.org/10.1371/journal.pone.0018370