The Non-Catalytic Carboxyl-Terminal Domain of ARFGAP1 Regulates Actin Cytoskeleton Reorganization by Antagonizing the Activation of Rac1

BACKGROUND: The regulation of the actin cytoskeleton and membrane trafficking is coordinated in mammalian cells. One of the regulators of membrane traffic, the small GTP-binding protein ARF1, also activates phosphatidylinositol kinases that in turn affect actin polymerization. ARFGAP1 is a GTPase ac...

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Detalles Bibliográficos
Autores principales: Siu, Ka Yu, Yu, Mei Kuen, Wu, Xinggang, Zong, Min, Roth, Michael G., Chan, Hsiao Chang, Yu, Sidney
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070737/
https://www.ncbi.nlm.nih.gov/pubmed/21483700
http://dx.doi.org/10.1371/journal.pone.0018458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070737/
https://www.ncbi.nlm.nih.gov/pubmed/21483700
http://dx.doi.org/10.1371/journal.pone.0018458

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