Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy depletion-induced suppression of mTORC1

Cell growth can be suppressed by stressful environments, but the role of stress pathways in this process is largely unknown. Here we show that a cascade of p38β mitogen activated protein kinase and p38 regulated/activated kinase (PRAK) plays a role in energy starvation-induced suppression of mammali...

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Detalles Bibliográficos
Autores principales: Zheng, Min, Wang, Yan-Hai, Wu, Xiao-Nan, Wu, Su-Qin, Lu, Bao-Ju, Dong, Meng-Qiu, Zhang, Hongbing, Sun, Peiqing, Lin, Sheng-Cai, Guan, Kun-Liang, Han, Jiahuai
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070924/
https://www.ncbi.nlm.nih.gov/pubmed/21336308
http://dx.doi.org/10.1038/ncb2168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070924/
https://www.ncbi.nlm.nih.gov/pubmed/21336308
http://dx.doi.org/10.1038/ncb2168

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