The Ribotoxin Restrictocin Recognizes Its RNA Substrate by Selective Engagement of Active Site Residues

[Image: see text] Restrictocin and related fungal endoribonucleases from the α-sarcin family site-specifically cleave the sarcin/ricin loop (SRL) on the ribosome to inhibit translation and ultimately trigger cell death. Previous studies showed that the SRL folds into a bulged-G motif and tetraloop,...

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Detalles Bibliográficos
Autores principales: Plantinga, Matthew J., Korennykh, Alexei V., Piccirilli, Joseph A., Correll, Carl C.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071035/
https://www.ncbi.nlm.nih.gov/pubmed/21417210
http://dx.doi.org/10.1021/bi1018336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071035/
https://www.ncbi.nlm.nih.gov/pubmed/21417210
http://dx.doi.org/10.1021/bi1018336

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