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High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection

Mannose-binding lectin (MBL) targets diverse microorganisms for phagocytosis and complement-mediated lysis by binding specific surface glycans. Although recombinant human MBL (rhMBL) trials have focused on reconstitution therapy, safety studies have identified no barriers to its use at higher levels...

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Detalles Bibliográficos
Autores principales: Michelow, Ian C., Lear, Calli, Scully, Corinne, Prugar, Laura I., Longley, Clifford B., Yantosca, L. Michael, Ji, Xin, Karpel, Marshall, Brudner, Matthew, Takahashi, Kazue, Spear, Gregory T., Ezekowitz, R. Alan B., Schmidt, Emmett V., Olinger, Gene G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071052/
https://www.ncbi.nlm.nih.gov/pubmed/21288816
http://dx.doi.org/10.1093/infdis/jiq025