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Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli
BACKGROUND: Isobutanol is a promising next-generation biofuel with demonstrated high yield microbial production, but the toxicity of this molecule reduces fermentation volumetric productivity and final titer. Organic solvent tolerance is a complex, multigenic phenotype that has been recalcitrant to...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071312/ https://www.ncbi.nlm.nih.gov/pubmed/21435272 http://dx.doi.org/10.1186/1475-2859-10-18 |