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Lysosomal positioning coordinates cellular nutrient responses

Mammalian target of rapamycin (mTOR) signalling and macroautophagy (henceforth autophagy) regulate numerous pathological and physiological processes including cellular responses to altered nutrient levels. However, the mechanisms regulating mTOR and autophagy remain incompletely understood. Lysosome...

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Detalles Bibliográficos
Autores principales: Korolchuk, Viktor I., Saiki, Shinji, Lichtenberg, Maike, Siddiqi, Farah H., Roberts, Esteban A., Imarisio, Sara, Jahreiss, Luca, Sarkar, Sovan, Futter, Marie, Menzies, Fiona M., O'Kane, Cahir J., Deretic, Vojo, Rubinsztein, David C.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071334/
https://www.ncbi.nlm.nih.gov/pubmed/21394080
http://dx.doi.org/10.1038/ncb2204