Cargando…
Lysosomal positioning coordinates cellular nutrient responses
Mammalian target of rapamycin (mTOR) signalling and macroautophagy (henceforth autophagy) regulate numerous pathological and physiological processes including cellular responses to altered nutrient levels. However, the mechanisms regulating mTOR and autophagy remain incompletely understood. Lysosome...
Autores principales: | Korolchuk, Viktor I., Saiki, Shinji, Lichtenberg, Maike, Siddiqi, Farah H., Roberts, Esteban A., Imarisio, Sara, Jahreiss, Luca, Sarkar, Sovan, Futter, Marie, Menzies, Fiona M., O'Kane, Cahir J., Deretic, Vojo, Rubinsztein, David C. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071334/ https://www.ncbi.nlm.nih.gov/pubmed/21394080 http://dx.doi.org/10.1038/ncb2204 |
Ejemplares similares
-
Complex Inhibitory Effects of Nitric Oxide on Autophagy
por: Sarkar, Sovan, et al.
Publicado: (2011) -
The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes
por: Jahreiss, Luca, et al.
Publicado: (2008) -
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease
por: Underwood, Benjamin R., et al.
Publicado: (2010) -
CCT complex restricts neuropathogenic protein aggregation via autophagy
por: Pavel, Mariana, et al.
Publicado: (2016) -
α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
por: Winslow, Ashley R., et al.
Publicado: (2010)