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Lipoxygenases and Poly(ADP-Ribose) Polymerase in Amyloid Beta Cytotoxicity

The 12/15-lipoxygenase(s) (LOX), poly(ADP-ribose) polymerase (PARP-1) activity and mitochondrial apoptosis inducing factor (AIF) protein in the amyloid β (Aβ) toxicity were investigated in PC12 cells that express either wild-type (APPwt) or double Swedish mutation (APPsw) forms of human Aβ precursor...

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Detalles Bibliográficos
Autores principales: Strosznajder, Joanna B., Cieslik, Magdalena, Cakala, Magdalena, Jesko, Henryk, Eckert, Anne, Strosznajder, Robert P.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071470/
https://www.ncbi.nlm.nih.gov/pubmed/21287270
http://dx.doi.org/10.1007/s11064-011-0412-7