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miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration

microRNAs function as genetic rheostats to control gene output. Based on their role as modulators, it has been postulated that microRNAs canalize development and provide genetic robustness. Here, we uncover a novel regulatory layer of chemokine signaling by microRNAs that confers genetic robustness...

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Detalles Bibliográficos
Autores principales: Staton, Alison A., Knaut, Holger, Giraldez, Antonio J.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071589/
https://www.ncbi.nlm.nih.gov/pubmed/21258340
http://dx.doi.org/10.1038/ng.758