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Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption

We report the first genome-wide association study of habitual caffeine intake. We included 47,341 individuals of European descent based on five population-based studies within the United States. In a meta-analysis adjusted for age, sex, smoking, and eigenvectors of population variation, two loci ach...

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Detalles Bibliográficos
Autores principales: Cornelis, Marilyn C., Monda, Keri L., Yu, Kai, Paynter, Nina, Azzato, Elizabeth M., Bennett, Siiri N., Berndt, Sonja I., Boerwinkle, Eric, Chanock, Stephen, Chatterjee, Nilanjan, Couper, David, Curhan, Gary, Heiss, Gerardo, Hu, Frank B., Hunter, David J., Jacobs, Kevin, Jensen, Majken K., Kraft, Peter, Landi, Maria Teresa, Nettleton, Jennifer A., Purdue, Mark P., Rajaraman, Preetha, Rimm, Eric B., Rose, Lynda M., Rothman, Nathaniel, Silverman, Debra, Stolzenberg-Solomon, Rachael, Subar, Amy, Yeager, Meredith, Chasman, Daniel I., van Dam, Rob M., Caporaso, Neil E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071630/
https://www.ncbi.nlm.nih.gov/pubmed/21490707
http://dx.doi.org/10.1371/journal.pgen.1002033