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Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation of Targets in the Mammalian Inner Ear

We have employed a novel approach for the identification of functionally important microRNA (miRNA)-target interactions, integrating miRNA, transcriptome and proteome profiles and advanced in silico analysis using the FAME algorithm. Since miRNAs play a crucial role in the inner ear, demonstrated by...

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Detalles Bibliográficos
Autores principales: Elkan-Miller, Tal, Ulitsky, Igor, Hertzano, Ronna, Rudnicki, Anya, Dror, Amiel A., Lenz, Danielle R., Elkon, Ran, Irmler, Martin, Beckers, Johannes, Shamir, Ron, Avraham, Karen B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071727/
https://www.ncbi.nlm.nih.gov/pubmed/21483685
http://dx.doi.org/10.1371/journal.pone.0018195