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Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

Retinoids are used clinically to treat a number of hyper-proliferative disorders and have been shown in experimental animals to attenuate vascular occlusive diseases, presumably through nuclear receptors bound to retinoic acid response elements (RARE) located in target genes. Here, we show that natu...

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Detalles Bibliográficos
Autores principales: Streb, Jeffrey W., Long, Xiaochun, Lee, Ting-Hein, Sun, Qiang, Kitchen, Chad M., Georger, Mary A., Slivano, Orazio J., Blaner, William S., Carr, Daniel W., Gelman, Irwin H., Miano, Joseph M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071728/
https://www.ncbi.nlm.nih.gov/pubmed/21483686
http://dx.doi.org/10.1371/journal.pone.0018538