Recombinant Complement Receptor 2 Radiolabeled with [(99m)Tc(CO)(3)](+) : A Potential New Radiopharmaceutical for Imaging Activated Complement

We describe the design and synthesis of a new Tc-99m labeled bioconjugate for imaging activated complement, based on Short Consensus Repeats 1 and 2 of Complement Receptor 2 (CR2), the binding domain for C3d. To avoid non specific modification of CR2 and the potential for modifying lysine residues c...

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Detalles Bibliográficos
Autores principales: Badar, Adam, DeFreitas, Sarah, McDonnell, James M., Yahya, Norhakim, Thakor, David, Razavi, Reza, Smith, Richard, Sacks, Steven, Mullen, Gregory E. D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071809/
https://www.ncbi.nlm.nih.gov/pubmed/21494666
http://dx.doi.org/10.1371/journal.pone.0018275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071809/
https://www.ncbi.nlm.nih.gov/pubmed/21494666
http://dx.doi.org/10.1371/journal.pone.0018275

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