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Minocycline Inhibition of Monocyte Activation Correlates with Neuronal Protection in SIV NeuroAIDS

BACKGROUND: Minocycline is a tetracycline antibiotic that has been proposed as a potential conjunctive therapy for HIV-1 associated cognitive disorders. Precise mechanism(s) of minocycline's functions are not well defined. METHODS: Fourteen rhesus macaques were SIV infected and neuronal metabol...

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Detalles Bibliográficos
Autores principales: Campbell, Jennifer H., Burdo, Tricia H., Autissier, Patrick, Bombardier, Jeffrey P., Westmoreland, Susan V., Soulas, Caroline, González, R. Gilberto, Ratai, Eva-Maria, Williams, Kenneth C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071838/
https://www.ncbi.nlm.nih.gov/pubmed/21494695
http://dx.doi.org/10.1371/journal.pone.0018688