Genetic deficiency of aldose reductase counteracts the development of diabetic nephropathy in C57BL/6 mice

AIMS/HYPOTHESIS: The aim of the study was to investigate the effects of genetic deficiency of aldose reductase in mice on the development of key endpoints of diabetic nephropathy. METHODS: A line of Ar (also known as Akr1b3)-knockout (KO) mice, a line of Ar-bitransgenic mice and control C57BL/6 mice...

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Detalles Bibliográficos
Autores principales: Liu, H., Luo, Y., Zhang, T., Zhang, Y., Wu, Q., Yuan, L., Chung, S. S. M., Oates, P. J., Yang, J. Y.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071933/
https://www.ncbi.nlm.nih.gov/pubmed/21267539
http://dx.doi.org/10.1007/s00125-011-2045-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071933/
https://www.ncbi.nlm.nih.gov/pubmed/21267539
http://dx.doi.org/10.1007/s00125-011-2045-4

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