The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

AIMS/HYPOTHESIS: We investigated the molecular mechanism by which the human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells in diabetic db/db mice. METHODS: Male db/db and m/m mice aged 10 weeks received liraglutide or vehicle for 2 days or 2 weeks. In addition to morpho...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimoda, M., Kanda, Y., Hamamoto, S., Tawaramoto, K., Hashiramoto, M., Matsuki, M., Kaku, K.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071950/
https://www.ncbi.nlm.nih.gov/pubmed/21340625
http://dx.doi.org/10.1007/s00125-011-2069-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071950/
https://www.ncbi.nlm.nih.gov/pubmed/21340625
http://dx.doi.org/10.1007/s00125-011-2069-9

Ejemplares similares