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Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington’s Disease
Huntington’s disease (HD) is a progressive neurodegenerative disease marked by psychiatric and motor problems. Recently, these findings have been extended to deficits in sleep and circadian function that can be observed in HD patients and in HD mouse models, with abnormal sleep patterns correlating...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072044/ https://www.ncbi.nlm.nih.gov/pubmed/21479110 http://dx.doi.org/10.1371/currents.RRN1225 |