The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain

CFP1 is a CXXC domain-containing protein and an essential component of the SETD1 histone H3K4 methyltransferase complex. CXXC domain proteins direct different chromatin-modifying activities to various chromatin regions. Here, we report crystal structures of the CFP1 CXXC domain in complex with six d...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Bian, Chuanbing, Lam, Robert, Dong, Aiping, Min, Jinrong
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072069/
https://www.ncbi.nlm.nih.gov/pubmed/21407193
http://dx.doi.org/10.1038/ncomms1237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072069/
https://www.ncbi.nlm.nih.gov/pubmed/21407193
http://dx.doi.org/10.1038/ncomms1237

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