Presynaptic CLC-3 Determines Quantal Size of Inhibitory Transmission in the Hippocampus

The absence of the chloride channel CLC-3 in Clcn3(−/−) mice results in hippocampal degeneration with a distinct temporal-spatial sequence reminiscent of neuronal loss in temporal lobe epilepsy. We examined how the loss of CLC-3 might impact GABAergic synaptic transmission in the hippocampus. An ele...

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Detalles Bibliográficos
Autores principales: Riazanski, Vladimir, Deriy, Ludmila V., Shevchenko, Pavel D., Le, Brandy, Gomez, Erwin A., Nelson, Deborah J.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072292/
https://www.ncbi.nlm.nih.gov/pubmed/21378974
http://dx.doi.org/10.1038/nn.2775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072292/
https://www.ncbi.nlm.nih.gov/pubmed/21378974
http://dx.doi.org/10.1038/nn.2775

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