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Molecular modeling and in silico characterization of Mycobacterium tuberculosis TlyA: Possible misannotation of this tubercle bacilli-hemolysin

BACKGROUND: The TlyA protein has a controversial function as a virulence factor in Mycobacterium tuberculosis (M. tuberculosis). At present, its dual activity as hemolysin and RNA methyltransferase in M. tuberculosis has been indirectly proposed based on in vitro results. There is no evidence howeve...

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Detalles Bibliográficos
Autores principales: Arenas, Nelson E, Salazar, Luz M, Soto, Carlos Y, Vizcaíno, Carolina, Patarroyo, Manuel E, Patarroyo, Manuel A, Gómez, Arley
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072309/
https://www.ncbi.nlm.nih.gov/pubmed/21443791
http://dx.doi.org/10.1186/1472-6807-11-16