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Fast local fragment chaining using sum-of-pair gap costs

BACKGROUND: Fast seed-based alignment heuristics such as BLAST and BLAT have become indispensable tools in comparative genomics for all studies aiming at the evolutionary relations of proteins, genes, and non-coding RNAs. This is true in particular for the large mammalian genomes. The sensitivity an...

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Detalles Bibliográficos
Autores principales: Otto, Christian, Hoffmann, Steve, Gorodkin, Jan, Stadler, Peter F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072320/
https://www.ncbi.nlm.nih.gov/pubmed/21418573
http://dx.doi.org/10.1186/1748-7188-6-4