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Fast local fragment chaining using sum-of-pair gap costs
BACKGROUND: Fast seed-based alignment heuristics such as BLAST and BLAT have become indispensable tools in comparative genomics for all studies aiming at the evolutionary relations of proteins, genes, and non-coding RNAs. This is true in particular for the large mammalian genomes. The sensitivity an...
Autores principales: | Otto, Christian, Hoffmann, Steve, Gorodkin, Jan, Stadler, Peter F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072320/ https://www.ncbi.nlm.nih.gov/pubmed/21418573 http://dx.doi.org/10.1186/1748-7188-6-4 |
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