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Multi-Scaled Explorations of Binding-Induced Folding of Intrinsically Disordered Protein Inhibitor IA3 to its Target Enzyme

Biomolecular function is realized by recognition, and increasing evidence shows that recognition is determined not only by structure but also by flexibility and dynamics. We explored a biomolecular recognition process that involves a major conformational change – protein folding. In particular, we e...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Wang, Yong, Chu, Xiakun, Hagen, Stephen J., Han, Wei, Wang, Erkang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072359/
https://www.ncbi.nlm.nih.gov/pubmed/21490720
http://dx.doi.org/10.1371/journal.pcbi.1001118