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Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies

Genome-wide association studies (GWAS) examine a large number of markers across the genome to identify associations between genetic variants and disease. Most published studies examine only single markers, which may be less informative than considering multiple markers and multiple genes jointly bec...

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Detalles Bibliográficos
Autores principales: Chen, Min, Cho, Judy, Zhao, Hongyu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072362/
https://www.ncbi.nlm.nih.gov/pubmed/21490723
http://dx.doi.org/10.1371/journal.pgen.1001353