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PDK1-Foxo1 in Agouti-Related Peptide Neurons Regulates Energy Homeostasis by Modulating Food Intake and Energy Expenditure
Insulin and leptin intracellular signaling pathways converge and act synergistically on the hypothalamic phosphatidylinositol-3-OH kinase/3-phosphoinositide-dependent protein kinase 1 (PDK1). However, little is known about whether PDK1 in agouti-related peptide (AGRP) neurons contributes to energy h...
Autores principales: | Cao, Yongheng, Nakata, Masanori, Okamoto, Shiki, Takano, Eisuke, Yada, Toshihiko, Minokoshi, Yasuhiko, Hirata, Yukio, Nakajima, Kazunori, Iskandar, Kristy, Hayashi, Yoshitake, Ogawa, Wataru, Barsh, Gregory S., Hosoda, Hiroshi, Kangawa, Kenji, Itoh, Hiroshi, Noda, Tetsuo, Kasuga, Masato, Nakae, Jun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072380/ https://www.ncbi.nlm.nih.gov/pubmed/21694754 http://dx.doi.org/10.1371/journal.pone.0018324 |
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