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De Novo Polymerase Activity and Oligomerization of Hepatitis C Virus RNA-Dependent RNA-Polymerases from Genotypes 1 to 5

Hepatitis C virus (HCV) shows a great geographical diversity reflected in the high number of circulating genotypes and subtypes. The response to HCV treatment is genotype specific, with the predominant genotype 1 showing the lowest rate of sustained virological response. Virally encoded enzymes are...

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Detalles Bibliográficos
Autores principales: Clemente-Casares, Pilar, López-Jiménez, Alberto J., Bellón-Echeverría, Itxaso, Encinar, José Antonio, Martínez-Alfaro, Elisa, Pérez-Flores, Ricardo, Mas, Antonio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072391/
https://www.ncbi.nlm.nih.gov/pubmed/21490973
http://dx.doi.org/10.1371/journal.pone.0018515