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De Novo Polymerase Activity and Oligomerization of Hepatitis C Virus RNA-Dependent RNA-Polymerases from Genotypes 1 to 5
Hepatitis C virus (HCV) shows a great geographical diversity reflected in the high number of circulating genotypes and subtypes. The response to HCV treatment is genotype specific, with the predominant genotype 1 showing the lowest rate of sustained virological response. Virally encoded enzymes are...
Autores principales: | Clemente-Casares, Pilar, López-Jiménez, Alberto J., Bellón-Echeverría, Itxaso, Encinar, José Antonio, Martínez-Alfaro, Elisa, Pérez-Flores, Ricardo, Mas, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072391/ https://www.ncbi.nlm.nih.gov/pubmed/21490973 http://dx.doi.org/10.1371/journal.pone.0018515 |
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