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Cbl Enforces Vav1 Dependence and a Restricted Pathway of T Cell Development

Extensive studies of pre-TCR- and TCR-dependent signaling have led to characterization of a pathway deemed essential for efficient T cell development, and comprised of a cascade of sequential events involving phosphorylation of Lck and ZAP-70, followed by phosphorylation of LAT and SLP-76, and subse...

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Detalles Bibliográficos
Autores principales: Chiang, Jeffrey, Hodes, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072394/
https://www.ncbi.nlm.nih.gov/pubmed/21490975
http://dx.doi.org/10.1371/journal.pone.0018542