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Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat

BACKGROUND: The Goto-Kakizaki (GK) rat is a well-studied non-obese spontaneous type 2 diabetes (T2D) animal model characterized by impaired glucose-stimulated insulin secretion (GSIS) in the pancreatic beta cells. MicroRNAs (miRNAs) are short regulatory RNAs involved in many fundamental biological p...

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Detalles Bibliográficos
Autores principales: Esguerra, Jonathan Lou S., Bolmeson, Caroline, Cilio, Corrado M., Eliasson, Lena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072418/
https://www.ncbi.nlm.nih.gov/pubmed/21490936
http://dx.doi.org/10.1371/journal.pone.0018613