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Fluoxetine reverses the memory impairment and reduction in proliferation and survival of hippocampal cells caused by methotrexate chemotherapy

RATIONALE: Adjuvant cancer chemotherapy can cause long-lasting, cognitive deficits. It is postulated that these impairments are due to these drugs targeting neural precursors within the adult hippocampus, the loss of which has been associated with memory impairment. OBJECTIVES: The present study inv...

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Detalles Bibliográficos
Autores principales: Lyons, Laura, ElBeltagy, Maha, Umka, Jariya, Markwick, Rachel, Startin, Carla, Bennett, Geoffrey, Wigmore, Peter
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072503/
https://www.ncbi.nlm.nih.gov/pubmed/21181126
http://dx.doi.org/10.1007/s00213-010-2122-2